Pub. Date : 2022
PMID : 35547368
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Monocarboxylate Transporter 1 May Benefit Cerebral Ischemia via Facilitating Lactate Transport From Glial Cells to Neurons. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |
2 | In this review, it provides a novel insight that MCT1 may protect brain from I/R injury via facilitating lactate transport from glial cells (such as, astrocytes and OLs) to neurons. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |
3 | It extensively discusses (1) the structure and localization of MCT1; (2) the regulation of MCT1 in lactate transport among astrocytes, OLs, and neurons; and (3) the regulation of MCT1 in the cellular response of lactate accumulation under ischemic attack. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |
4 | It extensively discusses (1) the structure and localization of MCT1; (2) the regulation of MCT1 in lactate transport among astrocytes, OLs, and neurons; and (3) the regulation of MCT1 in the cellular response of lactate accumulation under ischemic attack. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |
5 | It extensively discusses (1) the structure and localization of MCT1; (2) the regulation of MCT1 in lactate transport among astrocytes, OLs, and neurons; and (3) the regulation of MCT1 in the cellular response of lactate accumulation under ischemic attack. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |
6 | At last, this review concludes that MCT1, in cerebral ischemia, may improve lactate transport from glial cells to neurons, which subsequently alleviates cellular damage induced by lactate accumulation (mostly in glial cells), and meets the energy metabolism of neurons. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |
7 | At last, this review concludes that MCT1, in cerebral ischemia, may improve lactate transport from glial cells to neurons, which subsequently alleviates cellular damage induced by lactate accumulation (mostly in glial cells), and meets the energy metabolism of neurons. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |