Pub. Date : 2022 Jul
PMID : 35543162
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Antitumor effect of memantine is related to the formation of the splicing isoform of GLG1, a decoy FGF-binding protein. | Memantine | golgi glycoprotein 1 | Homo sapiens |
| 2 | However, the association between memantine and Golgi glycoprotein 1 (GLG1), an intracellular fibroblast growth factor receptor, in cancers has not yet been clarified. | Memantine | golgi glycoprotein 1 | Homo sapiens |
| 3 | However, the association between memantine and Golgi glycoprotein 1 (GLG1), an intracellular fibroblast growth factor receptor, in cancers has not yet been clarified. | Memantine | golgi glycoprotein 1 | Homo sapiens |
| 4 | The present study analyzed the expression and location of GLG1 in tumor cells treated with memantine. | Memantine | golgi glycoprotein 1 | Homo sapiens |
| 5 | Moreover, GLG1 spread in the cytosol of memantine-treated cells, whereas it localized in the Golgi apparatus in control cells. | Memantine | golgi glycoprotein 1 | Homo sapiens |
| 6 | Since GLG1 functions as a decoy FGF receptor, the modulation of GLG1 may prove to be one of the mechanisms underlying the cancer-suppressive effects of memantine. | Memantine | golgi glycoprotein 1 | Homo sapiens |