Title : Activation of the N-methyl-D-aspartate receptor contributes to orofacial neuropathic and inflammatory allodynia by facilitating calcium-calmodulin-dependent protein kinase II phosphorylation in mice.

Pub. Date : 2022 Jul

PMID : 35537568






1 Functional Relationships(s)
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1 These findings revealed novel molecular signaling pathways (NR2B-CaMKII-cAMP-ERK-CREB) in TG- and SpVc-derived latent subsequent peripheral and spinal central sensitization under nerve injury and inflammation, which might be beneficial for the treatment of orofacial allodynia. Cyclic AMP cAMP responsive element binding protein 1 Mus musculus