Title : Tofacitinib enhances IGF1 via inhibiting STAT6 transcriptionally activated-miR-425-5p to ameliorate inflammation in RA-FLS.

Pub. Date : 2022 May 10

PMID : 35536531






2 Functional Relationships(s)
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1 Tofacitinib significantly inhibited expression of pro-inflammatory factors including tumor necrosis factor-alpha (TNF-alpha), vascular endothelial growth factor A, matrix metalloproteinase 1, matrix metalloproteinase 3, interleukin-6 and interferon gamma in RA-FLS cells. tofacitinib tumor necrosis factor Homo sapiens
2 Tofacitinib significantly inhibited expression of pro-inflammatory factors including tumor necrosis factor-alpha (TNF-alpha), vascular endothelial growth factor A, matrix metalloproteinase 1, matrix metalloproteinase 3, interleukin-6 and interferon gamma in RA-FLS cells. tofacitinib tumor necrosis factor Homo sapiens