Title : The AMPK-related kinase NUAK2 suppresses glutathione peroxidase 4 expression and promotes ferroptotic cell death in breast cancer cells.

Pub. Date : 2022 May 6

PMID : 35523770






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Lipid hydroperoxides are neutralized in cells by glutathione peroxidase 4 (GPX4) and inhibitors of GPX4 are potent ferroptosis inducers with therapeutic potential in cancer. Lipid Peroxides glutathione peroxidase 4 Homo sapiens
2 Lipid hydroperoxides are neutralized in cells by glutathione peroxidase 4 (GPX4) and inhibitors of GPX4 are potent ferroptosis inducers with therapeutic potential in cancer. Lipid Peroxides glutathione peroxidase 4 Homo sapiens
3 Lipid hydroperoxides are neutralized in cells by glutathione peroxidase 4 (GPX4) and inhibitors of GPX4 are potent ferroptosis inducers with therapeutic potential in cancer. Lipid Peroxides glutathione peroxidase 4 Homo sapiens