Title : Distinct effects of Na+ and Li+ on the induction of morphological changes in A431 cells mediated by epidermal growth factor.

Pub. Date : 1987 Feb

PMID : 3552262






3 Functional Relationships(s)
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1 Addition of vanadate to the NaCl solution also induced fingerlike extensions in cells treated with EGF. Vanadates epidermal growth factor Homo sapiens
2 These findings indicate that Li+, K+, PO4(3-) and vanadate are involved in the processes of EGF-induced morphological changes. Vanadates epidermal growth factor Homo sapiens
3 Since vanadate and Li+ have been shown to inhibit phosphatases, an EGF-dependent phosphorylation step may play an important role in the induction of the morphological changes observed. Vanadates epidermal growth factor Homo sapiens