Title : VHL Ser65 mutations enhance HIF2α signaling and promote epithelial-mesenchymal transition of renal cancer cells.

Pub. Date : 2022 May 3

PMID : 35505422






1 Functional Relationships(s)
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1 These mutations are predicted to cause Serine (c.193T > C) to Proline and Tryptophan (c.194C > G) substitution at residue 65 of VHL protein (p.Ser65Pro and Ser65Trp). Proline von Hippel-Lindau tumor suppressor Homo sapiens