Title : Analysis of senescence in gingival tissues and gingival fibroblast cultures.

Pub. Date : 2022 May 2

PMID : 35491709






2 Functional Relationships(s)
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1 MATERIALS AND METHODS: The production of senescence-associated beta-galactosidase (SA-beta-gal) and mRNA expression of p16, p21, interleukin (IL)-1beta, and tumor necrosis factor alpha (TNF-alpha) were evaluated in gingival tissues, gingival fibroblasts of 10- and 20-month-old C57BL/6NCrl mice, and multiple-passaged and hydrogen peroxide-stimulated human gingival fibroblasts (HGFs). Hydrogen Peroxide tumor necrosis factor Mus musculus
2 Compared to control cells, H2O2 treated HGF cells expressed higher levels of SA-beta-gal and p16, p21, IL-1beta, and TNF-alpha. Hydrogen Peroxide tumor necrosis factor Mus musculus