Title : MiR-223 inhibits hyperosmolarity-induced inflammation through downregulating NLRP3 activation in human corneal epithelial cells and dry eye patients.

Pub. Date : 2022 Jul

PMID : 35490837






2 Functional Relationships(s)
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1 We previously showed that increases in reactive oxygen species (ROS) generation upregulate NLRP3 inflammasome and inflammation through increases in both caspase-1 activity and rises in IL-1beta expression levels in animal models of dry eye (DE). Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens
2 We previously showed that increases in reactive oxygen species (ROS) generation upregulate NLRP3 inflammasome and inflammation through increases in both caspase-1 activity and rises in IL-1beta expression levels in animal models of dry eye (DE). Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens