Pub. Date : 2022 Feb 1
PMID : 35484753
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Additionally, RSL3 directly inhibits glutathione peroxidase 4 (GPX4) to detoxify L-OOH, and ferrous ions further catalyze the irreversible conversion of highly reactive lipid alkoxyl radicals (L-O ) from L-OOH to triggering waterfall-like cascade ferroptosis. | Lipid Peroxides | glutathione peroxidase 4 | Homo sapiens |
| 2 | Additionally, RSL3 directly inhibits glutathione peroxidase 4 (GPX4) to detoxify L-OOH, and ferrous ions further catalyze the irreversible conversion of highly reactive lipid alkoxyl radicals (L-O ) from L-OOH to triggering waterfall-like cascade ferroptosis. | Lipid Peroxides | glutathione peroxidase 4 | Homo sapiens |
| 3 | Additionally, RSL3 directly inhibits glutathione peroxidase 4 (GPX4) to detoxify L-OOH, and ferrous ions further catalyze the irreversible conversion of highly reactive lipid alkoxyl radicals (L-O ) from L-OOH to triggering waterfall-like cascade ferroptosis. | Lipid Peroxides | glutathione peroxidase 4 | Homo sapiens |
| 4 | Additionally, RSL3 directly inhibits glutathione peroxidase 4 (GPX4) to detoxify L-OOH, and ferrous ions further catalyze the irreversible conversion of highly reactive lipid alkoxyl radicals (L-O ) from L-OOH to triggering waterfall-like cascade ferroptosis. | Lipid Peroxides | glutathione peroxidase 4 | Homo sapiens |