Pub. Date : 2022 Apr 28
PMID : 35482362
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | At the same site, the 25-hydroxyvitamin D 24-hydroxlase enzyme encoded by CYP24A1 can hydroxylate 25-hydroxyvitamin D or calcitriol to deactivate the hormone. | Calcitriol | cytochrome P450 family 24 subfamily A member 1 | Homo sapiens |
| 2 | Plasma calcitriol levels are primarily determined by the regulated expression of CYP27B1 and CYP24A1. | Calcitriol | cytochrome P450 family 24 subfamily A member 1 | Homo sapiens |
| 3 | This occurs in response to parathyroid hormone (increases CYP27B1), calcitriol itself (decreases CYP27B1 and increases CYP24A1), calcitonin (increases or decreases CYP24A1 and increases CYP27B1), FGF23 (decreases CYP27B1 and increases CYP24A1) and potentially plasma calcium and phosphate levels themselves (mixed effects). | Calcitriol | cytochrome P450 family 24 subfamily A member 1 | Homo sapiens |
| 4 | This occurs in response to parathyroid hormone (increases CYP27B1), calcitriol itself (decreases CYP27B1 and increases CYP24A1), calcitonin (increases or decreases CYP24A1 and increases CYP27B1), FGF23 (decreases CYP27B1 and increases CYP24A1) and potentially plasma calcium and phosphate levels themselves (mixed effects). | Calcitriol | cytochrome P450 family 24 subfamily A member 1 | Homo sapiens |