Title : Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease.

Pub. Date : 2022 Apr 27

PMID : 35477935






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A joint X-ray/neutron structure of the Mpro/BBH-1 complex demonstrates that a Cys145 thiolate reaction with the inhibitor"s keto-warhead creates a negatively charged oxyanion. alpha-hexachlorocyclohexane NEWENTRY Severe acute respiratory syndrome-related coronavirus