Title : Synthesis and cholinesterase inhibitory activity study of Amaryllidaceae alkaloid analogues with N-methyl substitution.

Pub. Date : 2022 May 18

PMID : 35471452






1 Functional Relationships(s)
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1 In general, our products were more active against BuChE than against AChE, and it was noted that larger ligands should be prepared for future studies, since in some cases acetylcholine can still fit into the active site along with the bound ligand. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens