Title : Down-regulation of ABCB1 by Collateral Sensitivity Drugs Reverses Multidrug Resistance and Up-regulates Enolase I.

Pub. Date : 2022 Apr 26

PMID : 35471238






1 Functional Relationships(s)
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1 Recent developments in the studies of drug resistance have identified compounds such as verapamil and tamoxifen that specifically target ABCB1-expressing multidrug resistant (MDR) cells, through an ATP-dependent ROS-generating mechanism. Adenosine Triphosphate ATP binding cassette subfamily B member 1 Homo sapiens