Title : Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone.

Pub. Date : 2022 Apr 25

PMID : 35468896






1 Functional Relationships(s)
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1 Mechanistically, stimulation of PGR by progesterone activates the tyrosine kinase SRC, which phosphorylates the transcriptional factor IRF3 at Y107, leading to its activation and induction of antiviral genes. Progesterone progesterone receptor Mus musculus