Title : A dual-mechanism-driven electrochemiluminescence aptasensor for sensitive detection of β-amyloid peptides.

Pub. Date : 2022 May 5

PMID : 35468173






3 Functional Relationships(s)
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Protein Name
Organism
1 beta-Amyloid (Abeta) peptides can bind both Cu2+ and heme cofactors simultaneously to form heme-Cu2+-Abeta complexes, which are proposed to generate toxic partially reduced oxygen species (PROS, e.g., H2O2) and play a vital role in Alzheimer"s disease (AD). Hydrogen Peroxide amyloid beta precursor protein Homo sapiens
2 beta-Amyloid (Abeta) peptides can bind both Cu2+ and heme cofactors simultaneously to form heme-Cu2+-Abeta complexes, which are proposed to generate toxic partially reduced oxygen species (PROS, e.g., H2O2) and play a vital role in Alzheimer"s disease (AD). Hydrogen Peroxide amyloid beta precursor protein Homo sapiens
3 When the concentration of the target Abeta is low, the synergistic enhancement effect arising from K2S2O8 with in situ generated H2O2 is predominant, resulting in an increase in the ECL signal of g-C3N4. Hydrogen Peroxide amyloid beta precursor protein Homo sapiens