Title : PRDM16 Regulating Adipocyte Transformation and Thermogenesis: A Promising Therapeutic Target for Obesity and Diabetes.

Pub. Date : 2022

PMID : 35462933






1 Functional Relationships(s)
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1 For example, metformin promotes thermogenesis and alleviates obesity by activating the AMPK/alphaKG/PRDM16 signaling pathway; rosiglitazone alleviates obesity under the synergistic effect of PRDM16; resveratrol plays an antiobesity role by inducing the expression of PRDM16; liraglupeptide improves insulin resistance by inducing the expression of PRDM16; and mulberry leaves play an anti-inflammatory and antidiabetes role by activating the expression of brown fat cell marker genes (including PRDM16). Metformin insulin Homo sapiens