Title : [Effect of activation of Toll-like receptor signaling pathway of peripheral blood mononuclear cell in recombinant hepatitis B surface antigen immune response].

Pub. Date : 2022 Apr 10

PMID : 35443313






1 Functional Relationships(s)
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1 Conclusions: Poly I:C can activate TLR3/TRIF/NF-kappaB and TLR3/TRIF/IRF3 signaling pathway, promote the function of downstream signaling molecules, and then promote the maturation of DC, induce the immune responses of CD4+T cell, and promote the maturation and activation of B cells and the immune response of rHBsAg. Poly I-C nuclear factor kappa B subunit 1 Homo sapiens