Pub. Date : 2022 Apr 18
PMID : 35437791
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ROS-mediated activation of NLRP3 inflammasome associated with pyroptosis in Het-1A cells induced by the co-exposure of nitrosamines. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Pretreatment of reactive oxygen species scavenger N-acetyl-L-cysteine (NAC), particularly mitochondrial reactive oxygen species scavengers Mito-TEMPO, effectively inhibited the activation of NLRP3 inflammasome, suggesting that nitrosamines could mediate the activation of NLRP3 inflammasome via mitochondrial reactive oxygen species (mtROS). | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |