Title : P301L tau mutation leads to alterations of cell cycle, DNA damage response and apoptosis: Evidence for a role of tau in cancer.

Pub. Date : 2022 Jun

PMID : 35436464






1 Functional Relationships(s)
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1 Furthermore, mutated LCL displayed lower levels of phospho-Chk1 and phospho-Chk2 following hydrogen peroxide-induced oxidative stress, indicating a poorly effective DNA damage checkpoint, as well as reduced basal levels of p53. Hydrogen Peroxide tumor protein p53 Homo sapiens