Title : Regulation of genes for enzymes involved in fatty acid synthesis.

Pub. Date : 1986

PMID : 3541753






3 Functional Relationships(s)
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1 The levels of malic enzyme and fatty acid synthase are increased by feeding and decreased by starvation in liver in vivo and are increased by triiodothyronine and decreased by glucagon in hepatocytes in culture. Triiodothyronine fatty acid synthase Gallus gallus
2 In chick-embryo hepatocytes incubated in serum-free medium containing insulin, triiodothyronine causes a greater than 10-fold increase in levels of both malic enzyme and fatty acid synthase mRNAs. Triiodothyronine fatty acid synthase Gallus gallus
3 Kinetic and inhibitor experiments suggest a protein intermediate in the increases of malic enzyme and fatty acid synthase mRNAs caused by triiodothyronine. Triiodothyronine fatty acid synthase Gallus gallus