Title : YM155 Induces DNA Damage and Cell Death in Anaplastic Thyroid Cancer Cells by Inhibiting DNA Topoisomerase IIα at the ATP-Binding Site.

Pub. Date : 2022 Jun 1

PMID : 35405742






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Molecular modeling predicts binding for YM155 in the Top2alpha ATP binding site and identifies key amino acids for YM155-Top2alpha interaction. Adenosine Triphosphate DNA topoisomerase II alpha Homo sapiens