Title : Capsaicin ameliorates intermittent high glucose-mediated endothelial senescence via the TRPV1/SIRT1 pathway.

Pub. Date : 2022 Jun

PMID : 35405615






1 Functional Relationships(s)
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1 Capsaicin upregulated SIRT1 expression and downregulated the senescence marker, p21, thereby protecting endothelial cells from IHG-induced senescence as indicated by relieved G0/G1 phase arrest, improved cell viabilities, and reduced counts of senescent cells and ROS production. Capsaicin H3 histone pseudogene 16 Homo sapiens