Title : Effect of vitamin D on oxidative stress and serum inflammatory factors in the patients with type 2 diabetes.

Pub. Date : 2022 May

PMID : 35403296






2 Functional Relationships(s)
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1 After vitamin D supplementation for 90 days, T2DM patients had a 2-fold increase of GSH levels, from 2.72 +- 0.84 to 5.76 +- 3.19 mumol/ml, the concentration of MCP-1 decreased from 51.11 +- 20.86 to 25.42 +- 13.06 pg/ml, and IL-8 also decreased from 38.21 +- 21.76 to 16.05 +- 8.99 pg/ml. Vitamin D C-X-C motif chemokine ligand 8 Homo sapiens
2 In conclusion, our study demonstrated that vitamin D could regulate the production of GSH, thereby reducing the serum levels of MCP-1 and IL-8, alleviating oxidative stress and inflammation, providing evidence of the necessity and feasibility of adjuvant vitamin D treatment among patients with T2DM. Vitamin D C-X-C motif chemokine ligand 8 Homo sapiens