Title : Stress, Thyroid Dysregulation and Thyroid Cancer in Children and Adolescents. Proposed Impending Mechanisms.

Pub. Date : 2022 Apr 6

PMID : 35385843






1 Functional Relationships(s)
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1 Oxygen free radicals are capable of causing DNA damage via stimulation of the mitogen activating protein (MAP) kinase or phosphatidylinositol-3-kinase (PI3K/Akt) and/or nuclear factor kB (NFkB) pathways resulting in TC-associated-gene mutations such as RET/PTC, AKAP9-BRAF, NTRK1, RAASF, PIK3CA, and PTEN. Oxygen ret proto-oncogene Homo sapiens