Title : Colistin-induced pulmonary toxicity involves the activation of NOX4/TGF-β/mtROS pathway and the inhibition of Akt/mTOR pathway.

Pub. Date : 2022 May

PMID : 35378205






2 Functional Relationships(s)
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Protein Name
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1 Inhibition of autophagy or Akt pathways by chloroquine (CQ), 3-Methyladenine (3-MA) or LY294002 promoted colistin-induced mitochondrial damage, and caspase-dependent cellular apoptosis. 3-methyladenine thymoma viral proto-oncogene 1 Mus musculus
2 Inhibition of autophagy or Akt pathways by chloroquine (CQ), 3-Methyladenine (3-MA) or LY294002 promoted colistin-induced mitochondrial damage, and caspase-dependent cellular apoptosis. 3-methyladenine thymoma viral proto-oncogene 1 Mus musculus