Title : Tranexamic acid reduces endometrial cancer effects through the production of angiostatin.

Pub. Date : 2022

PMID : 35371322






3 Functional Relationships(s)
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1 Tranexamic acid reduces endometrial cancer effects through the production of angiostatin. Tranexamic Acid plasminogen Mus musculus
2 Furthermore, the macrophage counts and the levels of matrix metalloproteinase (MMP)-12 and angiostatin in tumor cells in the uterus increased compared to the corresponding values in the control group and further increased upon TA treatment. Tranexamic Acid plasminogen Mus musculus
3 The results of our study indicate that TA ameliorated the endometrial cancer induced by MNU and estradiol by regulating the macrophage/MMP-12/plasminogen/angiostatin signal transmission pathway. Tranexamic Acid plasminogen Mus musculus