Title : Diacerein ameliorates acetaminophen hepatotoxicity in rats via inhibiting HMGB1/TLR4/NF-κB and upregulating PPAR-γ signal.

Pub. Date : 2022 Apr 2

PMID : 35366176






1 Functional Relationships(s)
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1 Moreover, DIA dose-dependently alleviated oxidative stress status caused by APAP administration along with inflammatory markers, including the level of interleukin-1 beta (IL-1beta), myeloperoxidase (MPO), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6). diacerein interleukin 1 beta Rattus norvegicus