Pub. Date : 2022 Mar 28
PMID : 35351859
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Succinate levels were significantly reduced following treatment with inhibitors of succinate dehydrogenase (SDH), purine nucleotide cycle (PNC), and malate/aspartate shuttle (MAS), with the corresponding attenuation of oxidative stress, iron stress, neuronal damage, and cognitive impairment. | Succinic Acid | aminoadipate-semialdehyde synthase | Mus musculus |
| 2 | Succinate levels were significantly reduced following treatment with inhibitors of succinate dehydrogenase (SDH), purine nucleotide cycle (PNC), and malate/aspartate shuttle (MAS), with the corresponding attenuation of oxidative stress, iron stress, neuronal damage, and cognitive impairment. | Succinic Acid | aminoadipate-semialdehyde synthase | Mus musculus |
| 3 | Reversal catalysis of SDH through fumarate from the PNC and MAS pathways might be involved in hypoxia-induced succinate accumulation. | Succinic Acid | aminoadipate-semialdehyde synthase | Mus musculus |