Title : MiR-1656 targets GPX4 to trigger pyroptosis in broilers kidney tissues by activating NLRP3 inflammasome under Se deficiency.

Pub. Date : 2022 Jul

PMID : 35346830






1 Functional Relationships(s)
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1 This study showed that miR-1656 could increase the release of ROS by targeting GPX4, activated the NLRP3 inflammasome, and release the inflammatory factors IL-1beta and IL-18 to trigger pyroptosis in the kidney tissue of Se-deficient broilers. ros interleukin 1 alpha Homo sapiens