Title : ETC-1002 Attenuates Porphyromonas gingivalis Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells via the AMPK/NF-κB Pathway and Exerts Ameliorative Effects in Experimental Periodontitis in Mice.

Pub. Date : 2022

PMID : 35340409






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1 Results: ETC-1002 inhibited the production of proinflammatory cytokines, promoted AMPK phosphorylation, and decreased IkappaBalpha and NF-kappaB p65 phosphorylation levels in Pg-LPS-treated RAW264.7 macrophages. 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Mus musculus