Title : Effect of short-term cyclosporine administration in rats on renin-angiotensin and thromboxane A2: possible relevance to the reduction in glomerular filtration rate.

Pub. Date : 1986 Oct

PMID : 3531461






1 Functional Relationships(s)
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1 In conclusion the early reduction in GFR which follows daily administration of CyA in rats might be the result of a synergic action of angiotensin II and TxA2 on vascular tone and mesangial contraction which is not modulated by an increase in glomerular vasodilatory prostaglandins. Prostaglandins angiotensinogen Rattus norvegicus