Title : Insights into the hepatotoxicity of pyrene and 1-chloropyrene using an integrated approach of metabolomics and transcriptomics.

Pub. Date : 2022 Jul 10

PMID : 35307418






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Transcriptomics results showed that exposure to Pyr and 1-Cl-Pyr at 5 and 50 nM obviously altered the gene expression profiles, but did not significantly induce the expression of genes strongly related to the activation of aryl hydrocarbon receptor (AhR), such as CYP1A1, CYP1B1, AHR, ARNT. pyrene cytochrome P450 family 1 subfamily A member 1 Homo sapiens