Title : Characterization of the modification of Kelch-like ECH-associated protein 1 by different fumarates.

Pub. Date : 2022 May 21

PMID : 35306364






2 Functional Relationships(s)
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1 Although it has been revealed that DMF and MEF differentially modify specific Keap1 cysteine residues and result in the differential activation of Nrf2, how the modification of DMF and MEF impacts the biochemical properties of Keap1 has not been well characterized. Dimethyl Fumarate NFE2 like bZIP transcription factor 2 Homo sapiens
2 Although it has been revealed that DMF and MEF differentially modify specific Keap1 cysteine residues and result in the differential activation of Nrf2, how the modification of DMF and MEF impacts the biochemical properties of Keap1 has not been well characterized. Dimethyl Fumarate NFE2 like bZIP transcription factor 2 Homo sapiens