Title : Structural basis for recognition and transport of folic acid in mammalian cells.

Pub. Date : 2022 Jun

PMID : 35303537






2 Functional Relationships(s)
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1 Three different systems control folate uptake in the human body; folate receptors function to capture and internalise extracellular folates via endocytosis, whereas two major facilitator superfamily transporters, the reduced folate carrier (RFC; SLC19A1) and proton-coupled folate transporter (PCFT; SLC46A1) control the transport of folates across cellular membranes. Folic Acid solute carrier family 19 member 1 Homo sapiens
2 Three different systems control folate uptake in the human body; folate receptors function to capture and internalise extracellular folates via endocytosis, whereas two major facilitator superfamily transporters, the reduced folate carrier (RFC; SLC19A1) and proton-coupled folate transporter (PCFT; SLC46A1) control the transport of folates across cellular membranes. Folic Acid solute carrier family 19 member 1 Homo sapiens