Title : EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation.

Pub. Date : 2022 Feb

PMID : 35255604






1 Functional Relationships(s)
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1 We aimed to examine the effects of EW-7197, an inhibitor of TGF-beta type 1 receptor kinase (ALK5), in retarding the progression of DN, both in vivo, using a diabetic mouse model (db/db mice), and in vitro, in podocytes and mesangial cells. vactosertib transforming growth factor, beta receptor I Mus musculus