Pub. Date : 2022 Mar 4
PMID : 35246515
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The results demonstrated that TME secretes leptin, which induces LSC differentiation and increases testosterone production. | Testosterone | leptin | Homo sapiens |
| 2 | Leptin"s effects on LSC differentiation and testosterone production, however, are inversely concentration-dependent: positive at low doses and negative at higher doses. | Testosterone | leptin | Homo sapiens |
| 3 | Taken together, these findings identify leptin as a key paracrine factor released by cells within the TME that modulates LSC differentiation and testosterone release from mature Leydig cells, a finding with important clinical implications for TD. | Testosterone | leptin | Homo sapiens |