Title : Amelioration of hepatic steatosis by dietary essential amino acid-induced ubiquitination.

Pub. Date : 2022 Apr 21

PMID : 35245436






1 Functional Relationships(s)
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1 Leucine and isoleucine, two branched-chain essential amino acids, strongly bind to and activate the E3 ubiquitin ligase Ubr1, targeting Plin2 for degradation. Isoleucine Ubr1 ubiquitin ligase Drosophila melanogaster