Title : PKM2 Is Overexpressed in Glioma Tissues, and Its Inhibition Highly Increases Late Apoptosis in U87MG Cells With Low-density Specificity.

Pub. Date : 2022 Mar-Apr

PMID : 35241524






2 Functional Relationships(s)
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1 We found that the PKM2 inhibitor shikonin was effective against U87MG cells at a relatively low dose and was largely dependent on low cellular density compared to the effects of the anticancer drug vincristine. shikonin pyruvate kinase M1/2 Homo sapiens
2 Co-treatment with two PKM2 inhibitors, shikonin and compound 3K, increased the inhibitory effects. shikonin pyruvate kinase M1/2 Homo sapiens