Title : A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET.

Pub. Date : 2022 Mar 3

PMID : 35239034






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1 The versatility of the pretargeting approach was showcased in vitro using a series of fluorescein-binding bsAbs directed at various established cancer-associated targets, including the pan-carcinoma cell surface marker EpCAM, EGFR, melanoma marker MCSP (aka CSPG4), and immune checkpoint PD-L1, offering a range of potential future applications for this pretargeting platform. Fluorescein epidermal growth factor receptor Homo sapiens