Title : Deferoxamine Inhibits Acute Lymphoblastic Leukemia Progression through Repression of ROS/HIF-1α, Wnt/β-Catenin, and p38MAPK/ERK Pathways.

Pub. Date : 2022

PMID : 35237325






2 Functional Relationships(s)
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1 Deferoxamine Inhibits Acute Lymphoblastic Leukemia Progression through Repression of ROS/HIF-1alpha, Wnt/beta-Catenin, and p38MAPK/ERK Pathways. Deferoxamine mitogen-activated protein kinase 14 Mus musculus
2 In conclusion, DFO inhibited the proliferation and ALL xenograft tumor growth, obstructed the cell cycle, and induced apoptosis of ALL cells, probably via inactivating the ROS/HIF-1alpha, Wnt/beta-catenin, and p38MAPK/ERK signaling. Deferoxamine mitogen-activated protein kinase 14 Mus musculus