Title : A possible causal involvement of neuroinflammatory, purinergic P2X7 receptors in psychiatric disorders.

Pub. Date : 2022 Mar 2

PMID : 35236262






1 Functional Relationships(s)
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1 The co-activation of toll-like receptors 4 (TLR4) by lipopolysaccharide, a constituent of the cell membrane of gram negative bacteria, and the P2X7R by ATP leads to the generation and release of the pro-inflammatory cytokines interleukin-1beta (IL-1beta), IL-6, and tumor necrosis factor-alpha. Adenosine Triphosphate interleukin 1 alpha Homo sapiens