Title : Lipoxin A4 regulates M1/M2 macrophage polarization via FPR2-IRF pathway.

Pub. Date : 2022 Apr

PMID : 35235107






1 Functional Relationships(s)
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1 In cultured macrophages, LXA4 inhibited LPS-induced inflammatory polarization, thereby decreasing the release of proinflammatory cell factors (IL-1beta, IL-6, TNF-alpha) and increasing the release of anti-inflammatory cytokines (IL-4 and IL-10). lipoxin A4 interleukin 6 Mus musculus