Pub. Date : 2022
PMID : 35222795
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nuclear factor erythroid 2-related factor 2 (Nrf2), a regulator of redox homeostasis, is involved in the ameliorative effects of testosterone supplementation upon aging. | Testosterone | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 2 | Supplementation with testosterone to Nrf2 KO-GDX mice only ameliorated the alterations above but did not reverse them to sham level. | Testosterone | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 3 | Activation of Nrf2 might contribute to testosterone-upregulating mitochondrial biogenesis and mitochondrial dynamics in the SN during aging to produce efficient mitochondria for ATP production. | Testosterone | nuclear factor, erythroid derived 2, like 2 | Mus musculus |