Title : ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation.

Pub. Date : 2022 Feb 26

PMID : 35218410






1 Functional Relationships(s)
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1 The inhibition of NFkappaB using the pharmacological inhibitor or siRNA effectively relieved H2O2 treatment- or Padi2 knockdown-induced senescence and osteoblast dysfunction. Hydrogen Peroxide nuclear factor kappa B subunit 1 Homo sapiens