Pub. Date : 2022 Jan 29
PMID : 35214061
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells. | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 2 | Capsaicin-induced LKB1 phosphorylation was dependent on the transient receptor potential cation channel subfamily V member 1 (TRPV1), since TRPV1 knocked down by shRNA abolished LKB1 and AMPK phosphorylation in LKB1-expressing cells. | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 3 | Capsaicin-induced LKB1 phosphorylation was dependent on the transient receptor potential cation channel subfamily V member 1 (TRPV1), since TRPV1 knocked down by shRNA abolished LKB1 and AMPK phosphorylation in LKB1-expressing cells. | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 4 | Capsaicin-induced LKB1 phosphorylation was dependent on the transient receptor potential cation channel subfamily V member 1 (TRPV1), since TRPV1 knocked down by shRNA abolished LKB1 and AMPK phosphorylation in LKB1-expressing cells. | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 5 | Altogether, our results showed that capsaicin affected AMPK activity in an LKB1- and TRPV1-dependent fashion, linking TRPV1 with cell fate. | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 6 | Altogether, our results showed that capsaicin affected AMPK activity in an LKB1- and TRPV1-dependent fashion, linking TRPV1 with cell fate. | Capsaicin | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |