Pub. Date : 2022 Feb 16
PMID : 35209128
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The finding that the most common mitochondrial DNA mutation m.11778G>A/MT-ND4 (p.R340H) associated with Leber"s hereditary optic neuropathy (LHON) induces rotenone resistance has produced a long-standing debate, because it contrasts structural evidence showing that the ND4 subunit is far away from the quinone-reaction site in complex I, where rotenone acts. | quinone | mitochondrially encoded NADH dehydrogenase 4 | Homo sapiens |
2 | The finding that the most common mitochondrial DNA mutation m.11778G>A/MT-ND4 (p.R340H) associated with Leber"s hereditary optic neuropathy (LHON) induces rotenone resistance has produced a long-standing debate, because it contrasts structural evidence showing that the ND4 subunit is far away from the quinone-reaction site in complex I, where rotenone acts. | quinone | mitochondrially encoded NADH dehydrogenase 4 | Homo sapiens |