Title : Effective drug combinations in breast, colon and pancreatic cancer cells.

Pub. Date : 2022 Mar

PMID : 35197630






1 Functional Relationships(s)
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1 Our results show that irinotecan and CHEK1 inhibition have synergistic effects in microsatellite-stable or KRAS-TP53 double-mutant colon cancer cells, leading to apoptosis and suppression of tumour xenograft growth. Irinotecan tumor protein p53 Homo sapiens