Pub. Date : 2022 Jun
PMID : 35193822
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Thymidine phosphorylase (TP) catalyzes the reversible phosphorolysis of thymidine, maintaining nucleoside homeostasis for DNA repair and replication. | Thymidine | thymidine phosphorylase | Homo sapiens |
| 2 | Thymidine phosphorylase (TP) catalyzes the reversible phosphorolysis of thymidine, maintaining nucleoside homeostasis for DNA repair and replication. | Thymidine | thymidine phosphorylase | Homo sapiens |
| 3 | In many cancers TP is expressed at high levels and promotes thymidine catabolism, ultimately generating 2-deoxyribose (2dDR) that can support multiple procancer processes, including glycation of proteins, alternative metabolism, extracellular matrix remodeling, and angiogenesis. | Thymidine | thymidine phosphorylase | Homo sapiens |