Title : Objective assessment of adrenocortical carcinoma driver genes and their correlation with tumor pyruvate kinase M2.

Pub. Date : 2022 May 15

PMID : 35189247






1 Functional Relationships(s)
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1 Out of these, the most prominent genetic alterations (PRKAR-1A, CTNNB1, ZNRF3, TP53, CCNE1 and TERF2 genes) are linked with a glycolytic enzyme pyruvate kinase M2 (PKM2), which converts phosphoenolpyruvate (PEP) to pyruvate in the glycolytic pathway. Pyruvic Acid tumor protein p53 Homo sapiens